Lilith was the First Woman, cast aside by Adam, the First Man, and replaced with Eve after she refused to get on her knees and pay homage to Adam's manhood. After the Fall, Lilith was abandoned by Big J and Adam and would have died by starvation were it not for divine intervention. Lilith was saved by consuming Lucifer's blood, which birthed her into a different sort of creature altogether: a creature determined never to need for anything again. She soon took vengeance on Adam, but spared Eve, instead turning the Second Woman into a demon by forcing her to imbibe her blood. By this method, Lilith is largely responsible for the demon half-breeds walking the Earth.
Lilith eventually married Lucifer, though her motivations for this remain unknown. It is generally believed she felt some affection for him, but in the end, her ruthless hatred of men bore no exclusions. Her ultimate goal remains to overthrow Big J and seek her final revenge for being created as the perceived weaker sex.